peripheral nervous system — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T6579	Medetomidine hydrochloride	MPV785,Medetomidine HCl,Domitor	Adrenergic Receptor
	Medetomidine hydrochloride (MPV785) is a selective α2-adrenoceptor agonist, with Ki of 1.08 nM, exhibts 1620-fold selectivity over α1-adrenoceptor.		Adrenergic Receptor
T7748	Dermorphin TFA		Others , Opioid Receptor
	Dermorphin TFA is a new class of opioids-like peptides		Others , Opioid Receptor
T7404	Dermorphin		Opioid Receptor
	Dermorphin is agonist of μ-opioid receptor (MOR) agonist.		Opioid Receptor
TN2322	Yangambin		Calcium Channel , PAFR
	Yangambin is a selective antagonist of the cardiovascular effects of platelet activating factor (PAF); it has hypotensive effect, which is probably due to a peripheral vasodilatation that involves, at least, the inhibiti...		Calcium Channel , PAFR
T7656	Apelin-13
	Apelin-13 is a 13-amino acid peptide sequence found in the central and peripheral nervous system that is an endogenous ligand for the G protein-coupled receptor angiotensin II protein J (APJ), with an EC50 value of 0.37 ...
T2525	Alosetron hydrochloride	Lotronex,GR 68755C,GR 68755,GR 68755X	5-HT Receptor
	Alosetron hydrochloride (GR 68755) is the hydrochloride salt form of alosetron, a potent and selective 5-HT3 receptor antagonist. Alosetron blocks the actions of serotonin at 5-HT3 sites in the peripheral nervous system,...		5-HT Receptor
T3354	BIA 10-2474	BIA10-2474	FAAH , Autophagy
	BIA 10-2474 is a long-acting reversible inhibitor of fatty acid amide hydrolase (FAAH) that increases levels of the neurotransmitter anandamide in the central nervous system and in peripheral tissues (that is, the rest o...		FAAH , Autophagy
T0848	L-DOPA	Levodopa,3,4-Dihydroxyphenylalanine	Dopamine Receptor , Endogenous Metabolite
	L-DOPA (Levodopa) is an amino acid precursor of dopamine with antiparkinsonian properties. Levodopa is a prodrug that is converted to dopamine by DOPA decarboxylase and can cross the blood-brain barrier. When in the brai...		Dopamine Receptor , Endogenous Metabolite
T68095	Losulazine		Dopamine Receptor , Norepinephrine
	Losulazine is a peripheral sympathetic antihypertensive compound that can be taken orally. Losulazine causes relatively modest, transient depletion of dopamine and norepinephrine in brain regions protected by the blood-b...		Dopamine Receptor , Norepinephrine
T27179	Diniprofylline	Coreverum
	Diniprofylline, a phosphodiesterase inhibitor, has been used as a peripheral nervous system agent, a bronchodilator agent, and an anti-asthamtic agent.
T11323L	Frakefamide		Others
	Frakefamide is a potent analgesic that functions as a peripheral active μ-selective receptor agonist. It cannot penetrate the blood-brain barrier to enter the central nervous system.		Others
T68937	Carbidopa hydrochloride
	Carbidopa hydrochloride is a drug given to people with Parkinson's disease in order to inhibit peripheral metabolism of levodopa. This property is significant in that it allows a greater proportion of peripheral levodopa...
T11323	Frakefamide TFA (188196-22-7 free base)	Frakefamide TFA	Others
	Frakefamide is unable to penetrate the blood-brain-barrier and enter the central nervous system. Frakefamide TFA is a potent analgesic that acts as a peripheral active μ-selective receptor agonist.		Others
T73655	Frakefamide TFA
	Frakefamide TFA is a potent analgesic functioning as a μ-selective receptor agonist with peripheral activity. Notably, Frakefamide cannot cross the blood-brain barrier to enter the central nervous system [1] [2].
T75788	α-CGRP(human) TFA
	α-CGRP(human) TFA is a 37-amino acid regulatory neuropeptide that is extensively located within the central and peripheral nervous system, functioning as a potent vasodilator [1].
T82403	Fibronectin Type III Connecting Segment Fragment 1-25
	Fibronectin Type III Connecting Segment Fragment 1-25 is a peptide implicated in melanoma cell adhesion and critical for the development of the chicken peripheral nervous system [1] [2].
T37715	Galactosylcerebrosides (bovine)
	Galactosylcerebrosides (SGal-CB) are expressed by Schwann cells (SCs) in the peripheral nervous system (PNS) during the early stages of myelination, and their persistence in the sheath is critical for long-term maintenan...
TP1681	Neuropeptide Y (22-36)
	Neuropeptide Y (22-36), a 15 amino acid peptide, is a fragment of Neuropeptide Y.Neuropeptide Y (NPY) is a 36 amino-acid neuropeptide that is involved in various physiological and homeostatic processes in both the centra...
T71955	C3001a
	C3001a is a selective activator for TREK, against other two-pore domain K+(K2P) channels. C3001a binds to the cryptic binding site formed by P1 and TM4 in TREK-1. C3001a targets TREK channels in the peripheral nervous sy...
T71425	Noberastine maleate
	Noberastine maleate, a histamine H1 antagonist, has potent and specific peripheral antihistaminic activity. Noberastine, a furan derivative of nor-astemizole (an astemizole metabolite), has been shown to have a more rapi...